English:

The clove plant contains a large amount of plant cannabinoids. These natural compounds function in the bodies of mammals as signaling molecules for the many processes regulated by the ECS system. When the body has enough of these signaling molecules available, this system of transmitters and receptors can function optimally, facilitating a good exchange of signals from organs and tissues to the brain and back. This is important for keeping the body healthy.

Balance

The ECS system is all about balance. If there is an imbalance in the body, such as a wound on the skin or harmful bacteria in the gastrointestinal tract, the body wants to restore this balance as quickly as possible. To direct this recovery, various signals are sent throughout the body. The mental health of both humans and animals is also linked to the ECS. When there are insufficient signaling molecules in the body, a dog (or human) is less able to cope with stress, anxiety, and pain.

Reducing Anxiety

Research shows that plant cannabinoids (excluding THC from cannabis) can reduce and regulate feelings of anxiety. Learned anxiety reactions, such as those from trauma or past bad experiences, can be alleviated and eventually disappear through treatment with plant cannabinoids. The signaling molecules from the clove plant also fall under these plant cannabinoids. Clove extracts are not hallucinogenic, they do not make you high, and they contain no THC. Plant cannabinoids can positively influence the mental state, mood, and behavior of your dog. Additionally, the hormone system is indirectly positively affected by these signaling molecules. The good news is that it is not necessary to give very high doses of these substances. A smaller, consistently given dose often works best.

Cannabinoids for Pain

Since the discovery of the ECS system at the end of the last century, many studies have been conducted on the effects of cannabinoids. These studies have shown that supplements of plant cannabinoids (excluding THC) can have a beneficial effect on acute and chronic pain. This also explains why cannabinoids from clove can help with physical ailments such as arthritis and osteoarthritis.

Bronnen:

Calignano A, La Rana G, Giuffrida A, Piomelli D. Nature. Control of pain initiation by endogenous cannabinoids. 1998 Jul 16;394(6690):277-81. https://www.ncbi.nlm.nih.gov/pubmed/9685157

Papagianni, E.P., Stevenson, C.W. Cannabinoid Regulation of Fear and Anxiety: an Update. Curr Psychiatry Rep 21, 38 (2019). https://doi.org/10.1007/s11920-019-1026-z

Andrea J. Narayan, Luke A. Downey, Brooke Manning, Amie C. Hayley, Cannabinoid treatments for anxiety: A systematic review and consideration of the impact of sleep disturbance, Neuroscience & Biobehavioral Reviews, Volume 143, 2022, 104941, ISSN 0149-7634. https://doi.org/10.1016/j.neubiorev.2022.104941

Yanes, J. A., McKinnell, Z. E., Reid, M. A., Busler, J. N., Michel, J. S., Pangelinan, M. M., Sutherland, M. T., Younger, J. W., Gonzalez, R., & Robinson, J. L. (2019). Effects of cannabinoid administration for pain: A meta-analysis and meta-regression. Experimental and Clinical Psychopharmacology, 27(4), 370–382. https://doi.org/10.1037/pha0000281